When the organs and tissues of the rats were examined under a microscope, there was almost no difference between those who were given stevia and those who were not. Undertaken with a faculty member at the University of the Republic in Montevideo, the study was prompted by a rumor that Indian women in South America used the herb for contraceptive purposes. We conclude that stevioside at a dose as high as 2. The rats who received the stevioside weighed less than those in the control group. In Japanese, partial English translation provided , that laboratory chow containing up to 7. Kuc also notes something else: While the results of the Kuc study might appear at first glance to bear out such rumors, closer examination raises doubts about the methods that were used, and how they apply to the typical way in which stevia is consumed.
Typically, a biological effect such as what Kuc reported would be demonstrated by using a variety of doses to establish what is known as a dose-response relationship. Chronic toxicity study of dietary stevia extracts in F rats. The only problem is that, outside of the FDA, no one in the scientific community gives it credence. Mating was efficient and successful. Kuc also notes something else: Shokuhin Kogyo 18 20 , When the organs and tissues of the rats were examined under a microscope, there was almost no difference between those who were given stevia and those who were not. The study showed no significant difference in the average growth of the first generation of hamsters in the groups receiving stevioside — no matter what dosage they were given. More than 40 years old, one leaf of the Stevia will still sweeten a cup of coffee or tea enough to satisfy my sweet tooth…. Animals were fed the experimental diets for 56 days…There were no abnormalities relative to controls reported that were dose-related, except for a significant decrease in serum lactic dehydrogenase levels. Neither of these two subacute toxicity studies would predict any potential harm on ingestion of S. While the results of the Kuc study might appear at first glance to bear out such rumors, closer examination raises doubts about the methods that were used, and how they apply to the typical way in which stevia is consumed. There are no reports of any government agency in any of the above countries indicating any public health concern whatsoever in connection with the use of stevia in foods. For a period of weeks two years , three groups of lab rats — 50 males and 50 females — were tested. In summary, no growth or fertility abnormalities were found in hamsters of either sex. The third group, which served as the control, received no stevoiside. It was later informally translated by an FDA employee familiar with Portuguese. Their performance was equal to the controls. None of this common usage in foods has indicated any evidence of a safety problem. It appear to be extraordinarily safe. He further concedes that this finding, in itself does not constitute an important reason for keeping stevia off the U. In this well-chronicled history of stevia, no author has ever reported any adverse human health consequences associated with consumption of stevia leaf. The study also only utilized one dosage level. The rats who received the stevioside weighed less than those in the control group. As to the mating performance, all three generations performed the same, no matter which dose of stevioside they received.
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